SignalSilence ® p53 siRNA I
| Name | SignalSilence ® p53 siRNA I |
|---|---|
| Supplier | Cell Signaling Technology |
| Catalog | 6231 |
| Category | siRNA |
| Prices | $256.00 |
| Sizes | 300 µl (50-100 transfections) |
| Applications | Gene Silencing |
| Species Reactivities | Human |
| Gene | TP53 |
| Description | SignalSilence ® p53 siRNA I from Cell Signaling Technology (CST) allows the researcher to specifically inhibit p53 expression using RNA interference, a method whereby gene expression can be selectively silenced through the delivery of double stranded RNA molecules into the cell |
| Supplier Page | Shop |
Product images
Western blot analysis of extracts from HeLa cells, transfected with non-targeted (-) or SignalSilence ® p53 siRNA I (+), using p53 Antibody #9282 and p42 MAP Kinase (Erk2) Antibody #9108. The p53 antibody confirms silencing of p53 expression, while the p42 MAPK antibody was used to control for loading and specificity of p53 siRNA.
Fluorescent detection of SignalSilence ® Control siRNA (Fluorescein Conjugate) #6201 in living HeLa cells 24 hours post-transfection, demonstrating nearly 100% transfection efficiency.